Long-term imatinib diminishes ovarian reserve and impacts embryo quality

PURPOSE: Tyrosine kinase inhibitors (TKIs) such as imatinib are commonly used chemotherapeutics, but the effects of long-term treatments on reproductive outlook for cancer survivors are unknown. The purpose of this study was to examine the effects of long-term imatinib treatments on follicle develop...

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Bibliographic Details
Published in:J Assist Reprod Genet
Main Authors: Salem, Wael, Ho, Jacqueline R., Woo, Irene, Ingles, Sue A., Chung, Karine, Paulson, Richard J., McGinnis, Lynda K.
Format: Artigo
Language:Inglês
Published: Springer US 2020
Subjects:
Fertility Preservation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311628/
https://ncbi.nlm.nih.gov/pubmed/32372302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-020-01778-7
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