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DREAM-in-CDM Approach and Identification of a New Generation of Anti-inflammatory Drugs Targeting mPGES-1

Microsomal prostaglandin E2 synthase-1 (mPGES-1) is known as an ideal target for next generation of anti-inflammatory drugs without the side effects of currently available anti-inflammatory drugs. However, there has been no clinically promising mPGES-1 inhibitor identified through traditional drug d...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhou, Shuo, Zhou, Ziyuan, Ding, Kai, Yuan, Yaxia, Loftin, Charles, Zheng, Fang, Zhan, Chang-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311425/
https://ncbi.nlm.nih.gov/pubmed/32576928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67283-0
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