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Cathepsin B deficiency ameliorates liver lipid deposition, inflammatory cell infiltration, and fibrosis after diet-induced nonalcoholic steatohepatitis

Non-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease characterized by fat accumulation and inflammation in liver. Yet, the mechanistic insight and diagnostic and therapeutic options of NASH remain incompletely understood. This study tested the roles of cysteine...

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Detalhes bibliográficos
Publicado no:Transl Res
Main Authors: Fang, Wenqian, Deng, Zhiyong, Benadjaoud, Feriel, Yang, Chongzhe, Shi, Guo-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311307/
https://ncbi.nlm.nih.gov/pubmed/32434697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2020.04.011
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