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Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth

Glucose utilization increases in tumors, a metabolic process that is observed clinically by (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET). However, is increased glucose uptake important for tumor cells, and which transporters are implicated in vivo? In a genetically-engineere...

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Udgivet i:eLife
Main Authors: Contat, Caroline, Ancey, Pierre-Benoit, Zangger, Nadine, Sabatino, Silvia, Pascual, Justine, Escrig, Stéphane, Jensen, Louise, Goepfert, Christine, Lanz, Bernard, Lepore, Mario, Gruetter, Rolf, Rossier, Anouk, Berezowska, Sabina, Neppl, Christina, Zlobec, Inti, Clerc-Rosset, Stéphanie, Knott, Graham William, Rathmell, Jeffrey C, Abel, E Dale, Meibom, Anders, Meylan, Etienne
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311173/
https://ncbi.nlm.nih.gov/pubmed/32571479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53618
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