Effects of Renin-Angiotensin Inhibition on ACE2 and TMPRSS2 Expression: Insights into COVID-19

Angiotensin-converting enzyme 2 (ACE2), a component of the renin-angiotensin system, is a receptor for SARS-CoV-2, the virus that causes COVID-19. To determine whether the renin-angiotensin inhibition regulates ACE2 expression, either enalapril (an angiotensin-converting enzyme inhibitor) or losarta...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Wu, Congqing, Ye, Dien, Mullick, Adam E., Li, Zhenyu, Danser, A.H. Jan, Daugherty, Alan, Lu, Hong S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310632/
https://ncbi.nlm.nih.gov/pubmed/32587974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.08.137331
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