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FAK signaling in Cancer-Associated Fibroblasts promotes breast cancer cell migration and metastasis by exosomal miRNAs-mediated intercellular communication
Cancer-associated fibroblasts (CAFs) are activated fibroblasts that constitute the major components of tumor microenvironment (TME) and play crucial roles in tumor development and metastasis. Here, we generated fibroblast-specific inducible focal adhesion kinase (FAK) knockout (cKO) mice in a breast...
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| Udgivet i: | Oncogene |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7310603/ https://ncbi.nlm.nih.gov/pubmed/31988451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1162-2 |
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