A randomized single-dose, two-period crossover bioequivalence study of two fixed-dose Paracetamol/Orphenadrine combination preparations in healthy volunteers under fasted condition

BACKGROUND: Paracetamol/Orphenadrine is a fixed dose combination containing 35 mg orphenadrine and 450 mg paracetamol. It has analgesic and muscle relaxant properties and is widely available as generics. This study is conducted to investigate the relative bioavailability and bioequivalence between o...

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Detalhes bibliográficos
Publicado no:BMC Pharmacol Toxicol
Main Authors: Cheah, Kit Yee, Mah, Kar Yee, Pang, Lai Hui, Ng, Shi Min, Wong, Jia Woei, Tan, Siew Siew, Tan, Hong Zhe, Yuen, Kah Hay
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310552/
https://ncbi.nlm.nih.gov/pubmed/32576287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-020-00416-3
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