ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer

BACKGROUND: ZNF322A is an oncogenic transcription factor that belongs to the Cys2His2-type zinc-finger protein family. Accumulating evidence suggests that ZNF322A may contribute to the tumorigenesis of lung cancer, however, the ZNF322A-mediated downstream signaling pathways remain unknown. METHODS:...

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Udgivet i:J Biomed Sci
Main Authors: Cheung, Chantal Hoi Yin, Hsu, Chia-Lang, Lin, Tsai-Yu, Chen, Wei-Ting, Wang, Yi-Ching, Huang, Hsuan-Cheng, Juan, Hsueh-Fen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310457/
https://ncbi.nlm.nih.gov/pubmed/32576196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-00668-5
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