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Anti-tumor immunity by pathogen-specific CD8 T cells in the absence of cognate antigen recognition

Cancer prognosis often correlates with the number of tumor-infiltrating CD8 T-cells, but many of these cells recognize pathogens that commonly infect humans. The contribution of pathogen-specific ‘bystander’ CD8 T-cells to antitumor immunity remains largely unknown. Inflammatory cytokines are suffic...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Danahy, Derek B, Berton, Roger B, Badovinac, Vladimir P
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310247/
https://ncbi.nlm.nih.gov/pubmed/32051220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901172
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