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Up-regulation of GLI1 in vincristine-resistant rhabdomyosarcoma and Ewing sarcoma
BACKGROUND: The clinical significance of GLI1 expression either through canonical Hedgehog signal transduction or through non-canonical mechanisms in rhabdomyosarcoma (RMS) or Ewing sarcoma (EWS) is incompletely understood. We tested a role for Hedgehog (HH) signal transduction and GL11 expression i...
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| Veröffentlicht in: | BMC Cancer |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7310145/ https://ncbi.nlm.nih.gov/pubmed/32493277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06985-0 |
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