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Off-target Editing by CRISPR-guided DNA base editors
Base editing is a genome editing strategy that induces specific single nucleotide changes within genomic DNA. Two major DNA base editors, Cytosine base editors (CBEs) and Adenine base editors (ABEs), have been developed that consist of a Cas9 protein linked to a deaminase enzyme that catalyzes targe...
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| 出版年: | Biochemistry |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7309633/ https://ncbi.nlm.nih.gov/pubmed/31433621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00573 |
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