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Reducible branched ester-amine quadpolymers (rBEAQs) co-delivering plasmid DNA and RNA oligonucleotides enable CRISPR/Cas9 genome editing

Functional co-delivery of plasmid DNA and RNA oligonucleotides in the same nanoparticle system is challenging due to differences in their physical properties as well as their intracellular locations of function. In this study, we synthesized a series of reducible branched ester-amine quadpolymers (r...

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Publicat a:ACS Appl Mater Interfaces
Autors principals: Rui, Yuan, Wilson, David R., Sanders, Katie, Green, Jordan J.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309334/
https://ncbi.nlm.nih.gov/pubmed/30794383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.8b20206
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