Fiber Optic Particle Plasmon Resonance Biosensor for Label-Free Detection of Nucleic Acids and Its Application to HLA-B27 mRNA Detection in Patients with Ankylosing Spondylitis

We developed a label-free, real-time, and highly sensitive nucleic acid biosensor based on fiber optic particle plasmon resonance (FOPPR). The biosensor employs a single-strand deoxyoligonucleotides (ssDNA) probe, conjugated to immobilized gold nanoparticles on the core surface of an optical fiber....

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Bibliographic Details
Published in:Sensors (Basel)
Main Authors: Tseng, Yen-Ta, Li, Wan-Yun, Yu, Ya-Wen, Chiang, Chang-Yue, Liu, Su-Qin, Chau, Lai-Kwan, Lai, Ning-Sheng, Chou, Cheng-Chung
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7309088/
https://ncbi.nlm.nih.gov/pubmed/32492975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s20113137
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