Independent Prognostic Value of Intratumoral Heterogeneity and Immune Response Features by Automated Digital Immunohistochemistry Analysis in Early Hormone Receptor-Positive Breast Carcinoma

Immunohistochemistry (IHC) for ER, PR, HER2, and Ki67 is used to predict outcome and therapy response in breast cancer patients. The current IHC assessment, visual or digital, is based mostly on global biomarker expression levels in the tissue sample. In our study, we explored the prognostic value o...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Zilenaite, Dovile, Rasmusson, Allan, Augulis, Renaldas, Besusparis, Justinas, Laurinaviciene, Aida, Plancoulaine, Benoit, Ostapenko, Valerijus, Laurinavicius, Arvydas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308549/
https://ncbi.nlm.nih.gov/pubmed/32612954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00950
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