A new safety index based on intrapulse monitoring of ultra-harmonic cavitation during ultrasound-induced blood-brain barrier opening procedures

Ultrasound-induced blood-brain barrier (BBB) opening using microbubbles is a promising technique for local delivery of therapeutic molecules into the brain. The real-time control of the ultrasound dose delivered through the skull is necessary as the range of pressure for efficient and safe BBB openi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Novell, A., Kamimura, H. A. S., Cafarelli, A., Gerstenmayer, M., Flament, J., Valette, J., Agou, P., Conti, A., Selingue, E., Aron Badin, R., Hantraye, P., Larrat, B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308405/
https://ncbi.nlm.nih.gov/pubmed/32572103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66994-8
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