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Age, Sex and Overall Health, Measured As Frailty, Modify Myofilament Proteins in Hearts From Naturally Aging Mice

We investigated effects of age, sex and frailty on contractions, calcium transients and myofilament proteins to determine if maladaptive changes associated with aging were sex-specific and modified by frailty. Ventricular myocytes and myofilaments were isolated from middle-aged (~12 mos) and older (...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Kane, Alice E., Bisset, Elise S., Keller, Kaitlyn M., Ghimire, Anjali, Pyle, W. Glen, Howlett, Susan E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308399/
https://ncbi.nlm.nih.gov/pubmed/32572088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66903-z
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