Early-onset atrial fibrillation patients show reduced left ventricular ejection fraction and increased atrial fibrosis

Atrial fibrillation (AF) has traditionally been considered an electrical heart disease. However, genetic studies have revealed that the structural architecture of the heart also play a significant role. We evaluated the functional and structural consequences of harboring a titin-truncating variant (...

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Udgivet i:Sci Rep
Main Authors: Andreasen, Laura, Bertelsen, Litten, Ghouse, Jonas, Lundegaard, Pia R., Ahlberg, Gustav, Refsgaard, Lena, Rasmussen, Torsten B., Eiskjær, Hans, Haunsø, Stig, Vejlstrup, Niels, Svendsen, Jesper H., Olesen, Morten S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308347/
https://ncbi.nlm.nih.gov/pubmed/32572052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66671-w
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