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The His-Gly motif of acid-sensing ion channels resides in a reentrant ‘loop’ implicated in gating and ion selectivity

Acid-sensing ion channels (ASICs) are proton-gated members of the epithelial sodium channel/degenerin (ENaC/DEG) superfamily of ion channels and are expressed throughout the central and peripheral nervous systems. The homotrimeric splice variant ASIC1a has been implicated in nociception, fear memory...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Yoder, Nate, Gouaux, Eric
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308080/
https://ncbi.nlm.nih.gov/pubmed/32496192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56527
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