Cardiac sympathetic activation circumvents high-dose beta blocker therapy in part through release of neuropeptide Y

The sympathetic nervous system plays an important role in the occurrence of ventricular tachycardia (VT). Many patients, however, experience VT despite maximal doses of beta blocker therapy, possibly due to the effects of sympathetic cotransmitters such as neuropeptide Y (NPY). The purpose of this s...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Hoang, Jonathan D., Salavatian, Siamak, Yamaguchi, Naoko, Swid, Mohammed Amer, Vaseghi, Marmar
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7308065/
https://ncbi.nlm.nih.gov/pubmed/32493842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135519
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