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Effect of Pressure Increase on Macromolecules’ Adsorption in Ion Exchange Chromatography

[Image: see text] In this study a new method for evaluating the pressure effect on separations of oligonucleotides and proteins on an anion exchange column was developed. The pressure rise of up to 500 bar was attained by coupling restriction capillaries to the column outlet to minimize differences...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Kristl, Anja, Lukšič, Miha, Pompe, Matevž, Podgornik, Aleš
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307832/
https://ncbi.nlm.nih.gov/pubmed/32075366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b05729
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