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Control of endothelial tubulogenesis by Rab and Ral GTPases, and apical targeting of caveolin-1-labeled vacuoles

Here, we examine known GTPase regulators of vesicle trafficking events to assess whether they affect endothelial cell (EC) lumen and tube formation. We identify novel roles for the small GTPases Rab3A, Rab3B, Rab8A, Rab11A, Rab27A, RalA, RalB and caveolin-1 in co-regulating membrane trafficking even...

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Publicat a:PLoS One
Autors principals: Norden, Pieter R., Sun, Zheying, Davis, George E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307772/
https://ncbi.nlm.nih.gov/pubmed/32569321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235116
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