Generation of Transgenic Cynomolgus Monkeys Overexpressing the Gene for Amyloid-β Precursor Protein

Alzheimer’s disease (AD) is the most common cause of dementia and understanding its pathogenesis should lead to improved therapeutic and diagnostic methods. Although several groups have developed transgenic mouse models overexpressing the human amyloid-β precursor protein (APP) gene with AD mutation...

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Bibliographic Details
Published in:J Alzheimers Dis
Main Authors: Seita, Yasunari, Morimura, Toshifumi, Watanabe, Naoki, Iwatani, Chizuru, Tsuchiya, Hideaki, Nakamura, Shinichiro, Suzuki, Toshiharu, Yanagisawa, Daijiro, Tsukiyama, Tomoyuki, Nakaya, Masataka, Okamura, Eiichi, Muto, Masanaga, Ema, Masatsugu, Nishimura, Masaki, Tooyama, Ikuo
Format: Artigo
Language:Inglês
Published: IOS Press 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306892/
https://ncbi.nlm.nih.gov/pubmed/32250299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-191081
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