Generation of Transgenic Cynomolgus Monkeys Overexpressing the Gene for Amyloid-β Precursor Protein

Alzheimer’s disease (AD) is the most common cause of dementia and understanding its pathogenesis should lead to improved therapeutic and diagnostic methods. Although several groups have developed transgenic mouse models overexpressing the human amyloid-β precursor protein (APP) gene with AD mutation...

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Détails bibliographiques
Publié dans:J Alzheimers Dis
Auteurs principaux: Seita, Yasunari, Morimura, Toshifumi, Watanabe, Naoki, Iwatani, Chizuru, Tsuchiya, Hideaki, Nakamura, Shinichiro, Suzuki, Toshiharu, Yanagisawa, Daijiro, Tsukiyama, Tomoyuki, Nakaya, Masataka, Okamura, Eiichi, Muto, Masanaga, Ema, Masatsugu, Nishimura, Masaki, Tooyama, Ikuo
Format: Artigo
Langue:Inglês
Publié: IOS Press 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306892/
https://ncbi.nlm.nih.gov/pubmed/32250299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-191081
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