PI(4,5)P(2)-dependent regulation of exocytosis by amisyn, the vertebrate-specific competitor of synaptobrevin 2

The functions of nervous and neuroendocrine systems rely on fast and tightly regulated release of neurotransmitters stored in secretory vesicles through SNARE-mediated exocytosis. Few proteins, including tomosyn (STXBP5) and amisyn (STXBP6), were proposed to negatively regulate exocytosis. Little is...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Kondratiuk, Ilona, Jakhanwal, Shrutee, Jin, Jialin, Sathyanarayanan, Udhayabhaskar, Kroppen, Benjamin, Pobbati, Ajaybabu V., Krisko, Anita, Ashery, Uri, Meinecke, Michael, Jahn, Reinhard, Fasshauer, Dirk, Milosevic, Ira
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306819/
https://ncbi.nlm.nih.gov/pubmed/32467162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908232117
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