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A parallelized, automated platform enabling individual or sequential ChIP of histone marks and transcription factors

Despite its popularity, chromatin immunoprecipitation followed by sequencing (ChIP-seq) remains a tedious (>2 d), manually intensive, low-sensitivity and low-throughput approach. Here, we combine principles of microengineering, surface chemistry, and molecular biology to address the major limitat...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dainese, Riccardo, Gardeux, Vincent, Llimos, Gerard, Alpern, Daniel, Jiang, Jia Yuan, Meireles-Filho, Antonio Carlos Alves, Deplancke, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306797/
https://ncbi.nlm.nih.gov/pubmed/32461370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913261117
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