Dynamic competition for hexon binding between core protein VII and lytic protein VI promotes adenovirus maturation and entry

Adenovirus minor coat protein VI contains a membrane-disrupting peptide that is inactive when VI is bound to hexon trimers. Protein VI must be released during entry to ensure endosome escape. Hexon:VI stoichiometry has been uncertain, and only fragments of VI have been identified in the virion struc...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hernando-Pérez, Mercedes, Martín-González, Natalia, Pérez-Illana, Marta, Suomalainen, Maarit, Condezo, Gabriela N., Ostapchuk, Philomena, Gallardo, José, Menéndez, Margarita, Greber, Urs F., Hearing, Patrick, de Pablo, Pedro J., San Martín, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306765/
https://ncbi.nlm.nih.gov/pubmed/32467158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920896117
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