Unveiling Molecular Recognition of Sialoglycans by Human Siglec-10

Siglec-10 is an inhibitory I-type lectin selectively recognizing sialoglycans exposed on cell surfaces, involved in several patho-physiological processes. The key role Siglec-10 plays in the regulation of immune cell functions has made it a potential target for the development of immunotherapeutics...

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Publicat a:iScience
Autors principals: Forgione, Rosa Ester, Di Carluccio, Cristina, Guzmán-Caldentey, Juan, Gaglione, Rosa, Battista, Filomena, Chiodo, Fabrizio, Manabe, Yoshiyuki, Arciello, Angela, Del Vecchio, Pompea, Fukase, Koichi, Molinaro, Antonio, Martín-Santamaría, Sonsoles, Crocker, Paul R., Marchetti, Roberta, Silipo, Alba
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306591/
https://ncbi.nlm.nih.gov/pubmed/32629603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101231
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