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Impact of the Protein Data Bank on antineoplastic approvals
Open access to 3D structure information from the Protein Data Bank (PDB) facilitated discovery and development of >90% of the 79 new antineoplastic agents (54 small molecules, 25 biologics) with known molecular targets approved by the FDA 2010–2018. Analyses of PDB holdings, the scientific litera...
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| Publicado no: | Drug Discov Today |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7305983/ https://ncbi.nlm.nih.gov/pubmed/32068073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2020.02.002 |
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