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Time Course of Changes in Sorafenib-Treated Hepatocellular Carcinoma (HCC) Cells Suggests Involvement of Phospho-Regulated Signaling in Ferroptosis Induction
Ferroptosis is a form of regulated, non-apoptotic cell death characterized by excessive lipid peroxidation that can be triggered by inhibition of the cystine-glutamate antiporter, system X(c)(−). Sorafenib, an FDA-approved multi-kinase inhibitor drug that is used for treatment of hepatocellular carc...
Tallennettuna:
| Julkaisussa: | Proteomics |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7305944/ https://ncbi.nlm.nih.gov/pubmed/32336023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.202000006 |
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