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Trichloroethylene exposure alters dimethylated histone three lysine four in protein kinase A signaling pathway chromatin of rat sperm(†)

Histone three lysine four dimethylation (H3k4me2) in sperm is conserved across species and is linked to transgenerational epigenetic inheritance. To test whether H3K4me2 is a target for transgenerational inheritance of toxicity, a daily gavage bolus exposure of trichloroethylene (TCE) (1000 mg/kg/da...

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Detalhes bibliográficos
Publicado no:Biol Reprod
Main Authors: Stermer, Angela R, Wilson, Shelby K, Klein, David, Hall, Susan J, Boekelheide, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305791/
https://ncbi.nlm.nih.gov/pubmed/31426087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz155
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