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Glycan-specific precipitation of glycopeptides in high organic content sample solvents used in HILIC

The composition of a sample solvent has a crucial impact on separations in hydrophilic interaction liquid chromatography (HILIC). In this short communication, we studied the effect of an organic modifier in the sample solvent on the solubility of different tryptic glycopeptides of hemopexin and hapt...

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Dettagli Bibliografici
Pubblicato in:J Chromatogr B Analyt Technol Biomed Life Sci
Autori principali: Kozlik, Petr, Molnarova, Katarina, Jecmen, Tomas, Krizek, Tomas, Goldman, Radoslav
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305521/
https://ncbi.nlm.nih.gov/pubmed/32485649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2020.122196
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