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Post-mortem Diagnosis of Heme Oxygenase-1 Deficiency by Whole Exome Sequencing in an Iranian Child

Heme oxygenase-1 (HO-1) is an inducible enzyme involved in the catalysis of heme conversion into biliverdin. We describe a patient with a novel stop-gain mutation in the HMOX1 coding sequence resulting in HO-1 deficiency. A 17-month-old female with fever, tachypnea, and signs of respiratory distress...

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Detalhes bibliográficos
Publicado no:Int J Mol Cell Med
Main Authors: Tahghighi, Fatemeh, Parvaneh, Nima, Ziaee, Vahid
Formato: Artigo
Idioma:Inglês
Publicado em: Babol University of Medical Sciences 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305464/
https://ncbi.nlm.nih.gov/pubmed/32587840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22088/IJMCM.BUMS.8.4.300
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