Transcriptional Regulation of the Angptl8 Gene by Hepatocyte Nuclear Factor-1 in the Murine Liver

Brief refeeding times (~60 min) enhanced hepatic Angptl8 expression in fasted mice. We cloned the mouse Angptl8 promoter region to characterise this rapid refeeding-induced increase in hepatic Angptl8 expression. Deletion of the −309/−60 promoter region significantly attenuated basal promoter activi...

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Udgivet i:Sci Rep
Main Authors: Watanabe, Takuya, Ozawa, Atsushi, Masuda, Shinnosuke, Yoshino, Satoshi, Ishida, Emi, Kondo, Yuri, Matsumoto, Shunichi, Katano-Toki, Akiko, Horiguchi, Kazuhiko, Nakajima, Yasuyo, Yamada, Eijiro, Tomaru, Takuya, Saito, Tsugumichi, Ishii, Sumiyasu, Shibusawa, Nobuyuki, Okada, Shuichi, Satoh, Tetsurou, Yamada, Masanobu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305314/
https://ncbi.nlm.nih.gov/pubmed/32561878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66570-0
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