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Mass spectrometry reveals the chemistry of formaldehyde cross-linking in structured proteins
Whole-cell cross-linking coupled to mass spectrometry is one of the few tools that can probe protein–protein interactions in intact cells. A very attractive reagent for this purpose is formaldehyde, a small molecule which is known to rapidly penetrate into all cellular compartments and to preserve t...
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| Pubblicato in: | Nat Commun |
|---|---|
| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7305180/ https://ncbi.nlm.nih.gov/pubmed/32561732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16935-w |
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