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Mass spectrometry reveals the chemistry of formaldehyde cross-linking in structured proteins

Whole-cell cross-linking coupled to mass spectrometry is one of the few tools that can probe protein–protein interactions in intact cells. A very attractive reagent for this purpose is formaldehyde, a small molecule which is known to rapidly penetrate into all cellular compartments and to preserve t...

詳細記述

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書誌詳細
出版年:Nat Commun
主要な著者: Tayri-Wilk, Tamar, Slavin, Moriya, Zamel, Joanna, Blass, Ayelet, Cohen, Shon, Motzik, Alex, Sun, Xue, Shalev, Deborah E., Ram, Oren, Kalisman, Nir
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305180/
https://ncbi.nlm.nih.gov/pubmed/32561732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16935-w
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