Capturing transient antibody conformations with DNA origami epitopes

Revealing antibody-antigen interactions at the single-molecule level will deepen our understanding of immunology. However, structural determination under crystal or cryogenic conditions does not provide temporal resolution for resolving transient, physiologically or pathologically relevant functiona...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Zhang, Ping, Liu, Xiaoguo, Liu, Pi, Wang, Fei, Ariyama, Hirotaka, Ando, Toshio, Lin, Jianping, Wang, Lihua, Hu, Jun, Li, Bin, Fan, Chunhai
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305102/
https://ncbi.nlm.nih.gov/pubmed/32561744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16949-4
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