Combination vaccine based on citrullinated vimentin and enolase peptides induces potent CD4-mediated anti-tumor responses

BACKGROUND: Stress-induced post-translational modifications occur during autophagy and can result in generation of new epitopes and immune recognition. One such modification is the conversion of arginine to citrulline by peptidylarginine deiminase enzymes. METHODS: We used Human leukocyte antigen (H...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Brentville, Victoria A, Metheringham, Rachael L, Daniels, Ian, Atabani, Suha, Symonds, Peter, Cook, Katherine W, Vankemmelbeke, Mireille, Choudhury, Ruhul, Vaghela, Poonam, Gijon, Mohamed, Meiners, Ghislaine, Krebber, Willem-Jan, Melief, Cornelis J M, Durrant, Lindy G
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Clinical/Translational Cancer Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304843/
https://ncbi.nlm.nih.gov/pubmed/32561639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000560
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