Liquid-Ordered Phase Formation by Mammalian and Yeast Sterols: A Common Feature With Organizational Differences

Here, biophysical properties of membranes enriched in three metabolically related sterols are analyzed both in vitro and in vivo. Unlike cholesterol and ergosterol, the common metabolic precursor zymosterol is unable to induce the formation of a liquid ordered (l(o)) phase in model lipid membranes a...

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Udgivet i:Front Cell Dev Biol
Main Authors: Khmelinskaia, Alena, Marquês, Joaquim M. T., Bastos, André E. P., Antunes, Catarina A. C., Bento-Oliveira, Andreia, Scolari, Silvia, Lobo, Gerson M. da S., Malhó, Rui, Herrmann, Andreas, Marinho, H. Susana, de Almeida, Rodrigo F. M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304482/
https://ncbi.nlm.nih.gov/pubmed/32596234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00337
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