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Inhibition of Adenosine Pathway Alters Atrial Electrophysiology and Prevents Atrial Fibrillation
BACKGROUND: Adenosine leads to atrial action potential (AP) shortening through activation of adenosine 1 receptors (A(1)-R) and subsequent opening of G-protein-coupled inwardly rectifying K(+) channels. Extracellular production of adenosine is drastically increased during stress and ischemia. OBJECT...
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| Veröffentlicht in: | Front Physiol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7304385/ https://ncbi.nlm.nih.gov/pubmed/32595514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00493 |
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