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Implementing sequence-based antigenic distance calculation into immunological shape space model

BACKGROUND: In 2009, a novel influenza vaccine was distributed worldwide to combat the H1N1 influenza “swine flu” pandemic. However, antibodies induced by the vaccine display differences in their specificity and cross-reactivity dependent on pre-existing immunity. Here, we present a computational mo...

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Pubblicato in:BMC Bioinformatics
Autori principali: Anderson, Christopher S., Sangster, Mark Y., Yang, Hongmei, Mariani, Thomas J., Chaudhury, Sidhartha, Topham, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303933/
https://ncbi.nlm.nih.gov/pubmed/32560624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03594-3
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