A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

SARS-CoV-2 has caused the COVID-19 pandemic. There is an urgent need for physiological models to study SARS-CoV-2 infection using human disease-relevant cells. COVID-19 pathophysiology includes respiratory failure but involves other organ systems including gut, liver, heart, and pancreas. We present...

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Опубликовано в: :Cell Stem Cell
Главные авторы: Yang, Liuliu, Han, Yuling, Nilsson-Payant, Benjamin E., Gupta, Vikas, Wang, Pengfei, Duan, Xiaohua, Tang, Xuming, Zhu, Jiajun, Zhao, Zeping, Jaffré, Fabrice, Zhang, Tuo, Kim, Tae Wan, Harschnitz, Oliver, Redmond, David, Houghton, Sean, Liu, Chengyang, Naji, Ali, Ciceri, Gabriele, Guttikonda, Sudha, Bram, Yaron, Nguyen, Duc-Huy T., Cioffi, Michele, Chandar, Vasuretha, Hoagland, Daisy A., Huang, Yaoxing, Xiang, Jenny, Wang, Hui, Lyden, David, Borczuk, Alain, Chen, Huanhuan Joyce, Studer, Lorenz, Pan, Fong Cheng, Ho, David D., tenOever, Benjamin R., Evans, Todd, Schwartz, Robert E., Chen, Shuibing
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier Inc. 2020
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Short Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303620/
https://ncbi.nlm.nih.gov/pubmed/32579880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.06.015
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