Efficacy and safety of aerosolized intra-tracheal dornase alfa administration in patients with SARS-CoV-2-induced acute respiratory distress syndrome (ARDS): a structured summary of a study protocol for a randomised controlled trial

OBJECTIVES: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) may trigger severe pneumonia in coronavirus disease of 2019 (COVID-19) patients through release of damage-associated molecular patterns (DAMPs) and recruitment of neutrophils in the lungs. Activated neutrophils induce inflammat...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Desilles, J. P., Gregoire, C., Le Cossec, C., Lambert, J., Mophawe, O., Losser, M. R., Lambiotte, F., Le Tacon, S., Cantier, M., Engrand, N., Trouiller, P., Pottecher, J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303591/
https://ncbi.nlm.nih.gov/pubmed/32560746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-020-04488-8
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