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Genetic variants associated with alcohol dependence co-ordinate regulation of ADH genes in gastrointestinal and adipose tissues

GWAS studies have identified genetic variants associated with Alcohol Dependence (AD), but how they link to genes, their regulation and disease traits, remains largely unexplored. Here we integrated information on the 3D genome organization with expression quantitative loci (eQTLs) analysis, using C...

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Publicado en:Sci Rep
Main Authors: Hibberd, Rebecca, Golovina, Evgeniia, Farrow, Sophie, O’Sullivan, Justin M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303195/
https://ncbi.nlm.nih.gov/pubmed/32555468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66048-z
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