Adenosine-producing regulatory B cells in head and neck cancer

BACKGROUND: Multiple mechanisms of immunosuppression have been identified in the tumor microenvironment including regulatory B cells (B(reg)). Recently, we have shown that B(reg) suppress T cell function by production of adenosine (ADO). However, the autocrine effect of ADO on B cells and the role o...

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Dettagli Bibliografici
Pubblicato in:Cancer Immunol Immunother
Autori principali: Jeske, Sandra S., Brand, Matthias, Ziebart, Andreas, Laban, Simon, Doescher, Johannes, Greve, Jens, Jackson, Edwin K., Hoffmann, Thomas K., Brunner, Cornelia, Schuler, Patrick J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303082/
https://ncbi.nlm.nih.gov/pubmed/32146518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02535-6
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