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Non-canonical RNA-DNA differences and other human genomic features are enriched within very short tandem repeats

Very short tandem repeats bear substantial genetic, evolutional, and pathological significance in genome analyses. Here, we compiled a census of tandem mono-nucleotide/di-nucleotide/tri-nucleotide repeats (MNRs/DNRs/TNRs) in GRCh38, which we term “polytracts” in general. Of the human genome, 144.4 m...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Yu, Hui, Zhao, Shilin, Ness, Scott, Kang, Huining, Sheng, Quanhu, Samuels, David C., Oyebamiji, Olufunmilola, Zhao, Ying-yong, Guo, Yan
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302867/
https://ncbi.nlm.nih.gov/pubmed/32511223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007968
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