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Altered Cortical and Hippocampal Excitability in TgF344-AD Rats Modeling Alzheimer’s Disease Pathology

Current findings suggest that accumulation of amyloid-β (Aβ) and hyperphosphorylated tau in the brain disrupt synaptic function in hippocampal–cortical neuronal networks leading to impairment in cognitive and affective functions in Alzheimer’s disease (AD). Development of new disease-modifying AD dr...

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Publicat a:Cereb Cortex
Autors principals: Stoiljkovic, Milan, Kelley, Craig, Stutz, Bernardo, Horvath, Tamas L, Hajós, Mihály
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302691/
https://ncbi.nlm.nih.gov/pubmed/29920597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhy140
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