Relationship between Anti-Spike Protein Antibody Titers and SARS-CoV-2 In Vitro Virus Neutralization in Convalescent Plasma

Newly emerged pathogens such as SARS-CoV-2 highlight the urgent need for assays that detect levels of neutralizing antibodies that may be protective. We studied the relationship between anti-spike ectodomain (ECD) and anti-receptor binding domain (RBD) IgG titers, and SARS-CoV-2 virus neutralization...

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Udgivet i:bioRxiv
Main Authors: Salazar, Eric, Kuchipudi, Suresh V., Christensen, Paul A., Eagar, Todd N., Yi, Xin, Zhao, Picheng, Jin, Zhicheng, Long, S. Wesley, Olsen, Randall J., Chen, Jian, Castillo, Brian, Leveque, Christopher, Towers, Dalton M., Lavinder, Jason, Gollihar, Jimmy D., Cardona, Jose, Ippolito, Gregory C., Nissly, Ruth H., Bird, Ian M., Greenawalt, Denver, Rossi, Randall M., Gontu, Abinhay, Srinivasan, Sreenidhi, Poojary, Indira B., Cattadori, Isabella M., Hudson, Peter J., Joselyn, Nicole, Prugar, Laura, Huie, Kathleen, Herbert, Andrew, Bernard, David W., Dye, John, Kapur, Vivek, Musser, James M.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302218/
https://ncbi.nlm.nih.gov/pubmed/32577662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.08.138990
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