Relationship between Anti-Spike Protein Antibody Titers and SARS-CoV-2 In Vitro Virus Neutralization in Convalescent Plasma

Newly emerged pathogens such as SARS-CoV-2 highlight the urgent need for assays that detect levels of neutralizing antibodies that may be protective. We studied the relationship between anti-spike ectodomain (ECD) and anti-receptor binding domain (RBD) IgG titers, and SARS-CoV-2 virus neutralization...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Salazar, Eric, Kuchipudi, Suresh V., Christensen, Paul A., Eagar, Todd N., Yi, Xin, Zhao, Picheng, Jin, Zhicheng, Long, S. Wesley, Olsen, Randall J., Chen, Jian, Castillo, Brian, Leveque, Christopher, Towers, Dalton M., Lavinder, Jason, Gollihar, Jimmy D., Cardona, Jose, Ippolito, Gregory C., Nissly, Ruth H., Bird, Ian M., Greenawalt, Denver, Rossi, Randall M., Gontu, Abinhay, Srinivasan, Sreenidhi, Poojary, Indira B., Cattadori, Isabella M., Hudson, Peter J., Joselyn, Nicole, Prugar, Laura, Huie, Kathleen, Herbert, Andrew, Bernard, David W., Dye, John, Kapur, Vivek, Musser, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302218/
https://ncbi.nlm.nih.gov/pubmed/32577662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.08.138990
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