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Severe COVID-19 in the young and healthy: monogenic inborn errors of immunity?

Severe COVID-19 is rare in previously healthy individuals who are less than 50 years of age, affecting probably no more than 1 in 1,000 such infected individuals. We suggest that these patients may become critically ill because of monogenic inborn errors that disrupt protective immunity to SARS-CoV-...

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Pubblicato in:Nat Rev Immunol
Autori principali: Zhang, Shen-Ying, Zhang, Qian, Casanova, Jean-Laurent, Su, Helen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302118/
https://ncbi.nlm.nih.gov/pubmed/32555547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41577-020-0373-7
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