Omalizumab for Aspirin Hypersensitivity and Leukotriene Overproduction in Aspirin-exacerbated Respiratory Disease. A Randomized Controlled Trial

Rationale: Aspirin-exacerbated respiratory disease is characterized by severe asthma, nonsteroidal antiinflammatory drug hypersensitivity, nasal polyposis, and leukotriene overproduction. Systemic corticosteroid therapy does not completely suppress lifelong aspirin hypersensitivity. Omalizumab effic...

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Bibliographic Details
Published in:Am J Respir Crit Care Med
Main Authors: Hayashi, Hiroaki, Fukutomi, Yuma, Mitsui, Chihiro, Kajiwara, Keiichi, Watai, Kentaro, Kamide, Yosuke, Nakamura, Yuto, Hamada, Yuto, Tomita, Yasuhiro, Sekiya, Kiyoshi, Tsuburai, Takahiro, Izuhara, Kenji, Wakahara, Keiko, Hashimoto, Naozumi, Hasegawa, Yoshinori, Taniguchi, Masami
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2020
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301746/
https://ncbi.nlm.nih.gov/pubmed/32142372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201906-1215OC
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