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Antiviral Activity of Feline BCA2 Is Mainly Dependent on Its Interference With Proviral Transcription Rather Than Degradation of FIV Gag

Human BCA2/RNF115/Rabring7 (hBCA2) is a RING type E3 ubiquitin ligase with the ability of autoubiquitination or promoting protein ubiquitination. It also acts as a host restriction factor has BST2-dependent and BST2-independent antiviral activity to inhibit the release of HIV-1. In a previous study,...

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Bibliografske podrobnosti
izdano v:Front Microbiol
Main Authors: Qu, Meng, Wang, Weiran, Li, Weiting, Cao, Jiaming, Zhang, Xin, Wang, Chu, Wu, Jiaxin, Yu, Bin, Zhang, Haihong, Wu, Hui, Kong, Wei, Yu, Xianghui
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301684/
https://ncbi.nlm.nih.gov/pubmed/32595622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.01230
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