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Synthesis of 12-Membered Tetra-aza Macrocyclic Pyridinophanes Bearing Electron-Withdrawing Groups

The number of substituted pyridine pyridinophanes found in the literature is limited due to challenges associated with 12-membered macrocycle and modified pyridine synthesis. Most notably, the electrophilic character at the 4-position of pyridine in pyridinophanes presents a unique challenge for int...

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Pubblicato in:J Org Chem
Autori principali: Yepremyan, Akop, Mekhail, Magy A., Niebuhr, Brian P., Pota, Kristof, Sadagopan, Nishanth, Schwartz, Timothy M., Green, Kayla N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301646/
https://ncbi.nlm.nih.gov/pubmed/32208700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c00188
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