Mesenchymal stem cells transfected with sFgl2 inhibit the acute rejection of heart transplantation in mice by regulating macrophage activation

BACKGROUND: Mesenchymal stem cells (MSCs) have become a promising candidate for cell-based immune therapy for acute rejection (AR) after heart transplantation due to possessing immunomodulatory properties. In this study, we evaluated the efficacy of soluble fibronectin-like protein 2 (sFgl2) overexp...

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Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Gao, Chao, Wang, Xiaodong, Lu, Jian, Li, Zhilin, Jia, Haowen, Chen, Minghao, Chang, Yuchen, Liu, Yanhong, Li, Peiyuan, Zhang, Baotong, Du, Xuezhi, Qi, Feng
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301524/
https://ncbi.nlm.nih.gov/pubmed/32552823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01752-1
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